Non-Engineered Nanoparticles of C60
نویسندگان
چکیده
We discovered that rubbing bulk solids of C₆₀ between fingertips generates nanoparticles including the ones smaller than 20 nm. Considering the difficulties usually associated with nanoparticle production by pulverisation, formation of nanoparticles by such a mundane method is unprecedented and noteworthy. We also found that nanoparticles of C₆₀ could be generated from bulk solids incidentally without deliberate engineering of any sort. Our findings imply that there exist highly unusual human exposure routes to nanoparticles of C₆₀, and elucidating formation mechanisms of nanoparticles is crucial in assessing their environmental impacts.
منابع مشابه
Modulation of γ-Irradiation Induced ROS Responses by Engineered Fullerenes in Human Epidermal Keratinocytes
High-dose ionizing irradiations can cause acute tissue and organ damage, especially severe cutaneous lesions. These cutaneous injuries often result in further complications and incur high mortality. Therefore, it is critical to develop effective therapeutic approaches for acute high-dose ionizing irradiation injury. Intracellular reactive oxygen species (ROS) have been implicated in mediating i...
متن کاملEvaluation of the effects of fullerene C60 nanoparticles on oxidative stress parameters at liver and brain of normal rats
Background & Objective: The potent antioxidant property of fullerene C60 nanoparticles and their derivatives has been demonstrated in a wide range of in vitro and in vivo studies. Hence, we examined the effects of fullerene C60 on the oxidative stress parameters at brain and liver of rats in normal situation. Materials & Methods: The study was performed in two groups of Wistar rats (each group...
متن کاملInhalation toxicity and lung toxicokinetics of C60 fullerene nanoparticles and microparticles.
While several recent reports have described the toxicity of water-soluble C60 fullerene nanoparticles, none have reported the toxicity resulting from the inhalation exposures to C60 fullerene nanoparticles or microparticles. To address this knowledge gap, we exposed male rats to C60 fullerene nanoparticles (2.22 mg/m3, 55 nm diameter) and microparticles (2.35 mg/m3, 0.93 microm diameter) for 3 ...
متن کاملClick Coupling Fullerene onto Thermoresponsive Water-Soluble Diblock Copolymer and Homopolymer Chains at Defined Positions
We report on the synthesis of well-defined thermoresponsive water-soluble diblock copolymer and homopolymers functionalized with controlled numbers of C60 moieties at predetermined positions via the combination of atom transfer radical polymerization (ATRP) and click chemistry. Azide-containing polymer precursors including monoazide-terminated and R,R-diazide-terminated poly(N-isopropylacrylami...
متن کاملA large-scale association study for nanoparticle C60 uncovers mechanisms of nanotoxicity disrupting the native conformations of DNA/RNA
Nano-scale particles have attracted a lot of attention for its potential use in medical studies, in particular for the diagnostic and therapeutic purposes. However, the toxicity and other side effects caused by the undesired interaction between nanoparticles and DNA/RNA are not clear. To address this problem, a model to evaluate the general rules governing how nanoparticles interact with DNA/RN...
متن کامل